Flavonoid-3′,5′-hydroxylase fromPhalaenopsis: A Novel Member of Cytochrome P450s, its cDNA Cloning, Endogenous Expression and Molecular Modeling

Molecular cloning and functional heterol

Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3′-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis

✍ Hubert H. Pauli; Toni M. Kutchan 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 434 KB

## Summary Alkaloids derived from the tetrahydrobenzylisoquinoline alkaloid (__S__)‐__N__‐methylcoclaurine represent a vast and varied structural array of physiologically active molecules. These compounds range from the dimeric bisbenzylisoquinolines, such as the muscle relaxant (+)‐tubocurarine, t