## BACKGROUND. Prostate cancer, suspected by serum prostate-specific antigen (PSA) elevation and/or digital abnormalities, is not always evident on gray-scale or color Doppler transrectal ultrasound (TRUS). EchoGen (Sonus Pharmaceuticals, Inc., Bothell, WA), a blood vessel image enhancer able to v
Flash effect of contrast microbubbles by ultrasound exposure
โ Scribed by Keisuke Matsushita; Shintaro Beppu; Fuminobu Ishikura; Haruka Kobayashi; Yuho Teruo; Yasushi Kashiwagi; Sachiko Yagura
- Publisher
- Springer
- Year
- 2001
- Tongue
- Japanese
- Weight
- 760 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1346-4523
No coin nor oath required. For personal study only.
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## Purpose: Microbubble contrast agents are currently implemented in a variety of both clinical and preclinical ultrasound imaging studies. The therapeutic and diagnostic capabilities of these contrast agents are limited by their short inโvivo lifetimes, and research to lengthen their circulation t
## Abstract Evidence that microbubbles are the main sources of ultrasound contrast in injected solutions has been largely indirect. To investigate this directly, we examined freshly agitated indocyanine green, freshly agitated water, commercially prepared precision microbubbles (diameter 75 ยฑ 25 ฮผ)
The pressure of the ultrasound wave may limit the lonultrasound scatterers and provide varying degrees of echogenic gevity of microbubble-based contrast agents. This study evaluated contrast [4,5,7,10,11]. The intensity of the reflected signal is reliver enhancement over time as a function of transm