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FK506 impairs human resistance vessels reactivity in vitro

✍ Scribed by ROULLET, J


Book ID
116156603
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
256 KB
Volume
9
Category
Article
ISSN
0895-7061

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FK506 is currently under investigation as immunosuppressant after organ transplantation and in immune diseases. The structure of a demethylated metabolite 1 of FK506 isolated after in oitro metabolism by human-liver microsomes was established using two-dimensional homo-and heteronuclear NMR experime