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FK506 blocks activation of the intrinsic caspase cascade after optic nerve crush

✍ Scribed by Cynthia L. Grosskreutz; Virve A. Hänninen; Mina B. Pantcheva; Wei Huang; Nathaniel R. Poulin; Adam P. Dobberfuhl


Book ID
116456127
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
205 KB
Volume
80
Category
Article
ISSN
0014-4835

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## Abstract Protease‐activated receptors (PARs), 7‐transmembrane domain G protein‐coupled receptors, are involved in tissue degeneration and repair upon injury. We demonstrate the expression of all four PAR subtypes in the postnatal eye and in retina of the adult rat by reverse transcription‐polyme