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Fixation of epigenetic states in a population

✍ Scribed by Andrew D. Keller


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
347 KB
Volume
176
Category
Article
ISSN
0022-5193

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✦ Synopsis


Multiple steady-state levels of autoregulatory transcription factors constitute alternative epigenetic states, and could help specify the heritable phenotype of an organism. In this work, the inheritance of autoregulatory transcription factors through sexual reproduction is modeled to determine the conditions under which different alternative epigenetic states become fixed in a population. The influence of transient environmental perturbations on the fixation of states is discussed in the context of speciation.


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