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Five years after central nervous system irradiation of children with leukemia

✍ Scribed by manuel S. Verzosa; Rhomes J.A. Aur; Joseph V. Simone; H.Omar Hustu; Donald P. Pinkel

Publisher: Elsevier Science
Year: 1976
Tongue: English
Weight: 644 KB
Volume: 1
Category: Article
ISSN: 0360-3016
DOI: 10.1016/0360-3016(76)90042-0

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## Abstract ## BACKGROUND Although central nervous system (CNS) prophylaxis in patients with leukemia has reduced the incidence of CNS disease recurrence, it still is reported to occur in approximately 5–10% of cases, resulting in a median survival of 6 months. Craniospinal irradiation (CSI) has b