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Five New Cassane-Type Diterpenes from Caesalpinia crista

✍ Scribed by Zheng-Yi Yang; Yin-Hua Yin; Li-Hong Hu

Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
151 KB
Volume
92
Category
Article
ISSN
0018-019X

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✦ Synopsis

Introduction. -Caesalpinia crista L. (Fabaceae) is a well-known medicinal plant widely distributed in tropical and subtropical regions of Southeast Asia. This plant is locally known as Ka-Lain in Myanmar, and its seeds are used as an anthelmintic, antipyretic, anti-inflammatory, and antimalarial agent [1]. In Indonesia, it is known as Bagore, and a decoction of its roots has been used as a tonic and for the treatment of rheumatism and backache [2]. As a member of the genus Caesalpinia, it is a rich source of cassane-type furanoditerpenes and is reported to have antimalarial [3] [4], antiviral [5], and anticancer activities [6]. We have chemically investigated the seeds of Caesalpinia crista which resulted in the isolation of five new cassane diterpenes (1 -5; see Fig. 1). In this paper, we report the structure elucidation of these cassane-type diterpenes.

Results and Discussion. -Compound 1 was isolated as a colorless amorphous solid and its molecular formula was determined to be C 21 H 30 O 5 by HR-EI-MS. The IR Fig. 1. The structures of compounds 1 -7

πŸ“œ SIMILAR VOLUMES

Cassane-Type Diterpenes from the Seeds o
Cassane-Type Diterpenes from the Seeds of Caesalpinia crista
✍ Sarot Cheenpracha; Chatchanok Karalai; Chanita Ponglimanont; Kan Chantrapromma; πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 German βš– 73 KB

## Abstract A new dimer **1** and two new cassane‐type diterpenes **2** and **3**, designated taepeenin J–L, were isolated from the seeds of __Caesalpinia crista__ L. Compound **1** possesses a dimeric vouacapane skeleton. Their structures were elucidated on the basis of spectroscopic analysis.