Fissistigmatins A–D: Novel Type Natural Products with Flavonoid–Sesquiterpene Hybrid Structure from Fissistigma bracteolatum

✍ Scribed by Andrea Porzel; Trinh Phuong Lien; Jürgen Schmidt; Susanne Drosihn; Christoph Wagner; Kurt Merzweiler; Tran Van Sung; Günter Adam

• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 255 KB
• Volume: 56
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(99)01049-2

✦ Synopsis

From Fissistigma bracteolatum Chatt. (Annonaceae), a Vietnamese folk medicinal plant, the novel type natural products fissistigmatin A-D (1-4), being composed of a flavonoid and a sesquiterpene moiety, were isolated. Their structures were elucidated by extensive NMR techniques, MS, CD, molecular modelling calculations and X-ray analysis.