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Fission yeast Clp1p phosphatase regulates G2/M transition and coordination of cytokinesis with cell cycle progression

✍ Scribed by Susanne Trautmann; Benjamin A. Wolfe; Paul Jorgensen; Mike Tyers; Kathleen L. Gould; Dannel McCollum

Book ID: 114318364
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 674 KB
Volume: 11
Category: Article
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(01)00268-8

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## Abstract The tumor‐suppressor p53 is a multifunctional protein mainly responsible for maintaining genomic integrity. p53 induces its tumor‐suppressor activity by either causing cell‐cycle arrest (G~1~/S or G~2~/M) or inducing cells to undergo apoptosis. This function of wild‐type p53 as “guardia