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FISH and molecular analyses of chromosomal markers bearing genes amplification in adipose tissue tumors

✍ Scribed by F Pedeutour; A Forus; R Suijkerbuijk; U Van Haelst; JM Coindre; G Barcelo; C Turc-Carel


Book ID
119106267
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
63 KB
Volume
77
Category
Article
ISSN
0165-4608

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Genetic alterations in sporadic renal-ce
✍ H. Brauch; S. Pomer; T. Hieronymus; T. Schadt; H. LΓΆhrke; D. Komitowski πŸ“‚ Article πŸ“… 1994 πŸ› Springer-Verlag 🌐 English βš– 935 KB

On a genetic level, renal-cell carcinoma has been characterized by an abnormality on the short arm of chromosome 3 (3p), which suggests the inactivation of a tumor suppressor gene. One tumor suppressor gene at 3p, the von Hippel-Lindau disease gene, is implicated in tumor development of a whole spec