๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Fisetin, an Inhibitor of Cyclin-Dependent Kinase 6, Down-Regulates Nuclear Factor- B-Regulated Cell Proliferation, Antiapoptotic and Metastatic Gene Products through the Suppression of TAK-1 and Receptor-Interacting Protein-Regulated I B Kinase Activation

โœ Scribed by Sung, B.; Pandey, M. K.; Aggarwal, B. B.


Book ID
117998910
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2007
Tongue
English
Weight
696 KB
Volume
71
Category
Article
ISSN
0026-895X

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Although the cytokine-inducible transcription factor signal transducer and activator of transcription 5 (STAT5) promotes proliferation of a wide range of cell types, there are cell-specific and context-specific cases in which loss of STAT5 results in enhanced cell proliferation. Here, we report that