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First trimester screening for trisomy 21 in gestational week 8-10 by ADAM12-S as a maternal serum marker

✍ Scribed by Niels Tørring; Susan Ball; Dave Wright; Gaïané Sarkissian; Marie Guitton; Bruno Darbouret


Book ID
119904114
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
546 KB
Volume
8
Category
Article
ISSN
1477-7827

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In a study of 2923 normal pregnancies and 203 pregnancies affected by trisomy 21 we have shown a signi®cant difference in the median MoM of the markers: fetal nuchal translucency, maternal serum free b-hCG and PAPP-A in the presence of a female fetus compared with a male fetus. For maternal serum fr