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First-trimester prenatal sonographic diagnosis of omphalocele-exstrophy-imperforate anus-spinal defects complex

✍ Scribed by Joseph R. Wax; Michael G. Pinette; Rosemarie Smith; Angelina Cartin; Jacquelyn Blackstone

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
174 KB
Volume
37
Category
Article
ISSN
0091-2751

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✦ Synopsis

Abstract

We describe a case of omphalocele‐exstrophy‐imperforate anus‐spinal defects (OEIS) diagnosed at 13 weeks' gestation by ultrasound detection of a large multilocular ventral wall mass into which inserted the umbilical cord, and thoracic hemivertebrae with kyphoscoliosis. Subsequent sonographic examinations at 16 and 19 weeks revealed evolution of the ventral wall mass into a classic omphalocele. Clinicians should recognize the significance of a large multicystic ventral wall mass, which should lead to a search for other anomalies suggestive of OEIS complex. © 2008 Wiley Periodicals, Inc. J Clin Ultrasound, 2009

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The omphalocele-exstrophy-imperforate anus-spinal defects (OEIS) complex is a consistent and recognizable pattern of midline abdominal and pelvic defects. It is rare, affecting 1 in 200,000 to 400,000 pregnancies and is even rarer in twin gestations. This is an autopsy study of OEIS complex in monoz