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First trimester maternal serum AFP and total hCG in aneuploidies other than trisomy 21

โœ Scribed by K. Spencer; V. Heath; N. Flack; C. Ong; K. H. Nicolaides


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
62 KB
Volume
20
Category
Article
ISSN
0197-3851

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Is maternal serum total hCG a marker of
โœ Kevin Spencer; Esther Berry; Jennifer A. Crossley; David A. Aitken; Kypros H. Ni ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 89 KB ๐Ÿ‘ 2 views

In a study of 130 ยฎrst trimester cases of trisomy 21 and 959 controls we have shown that the median MoM for alpha-fetoprotein (AFP) is lower (0.82) and that for total human chorionic gonadotrophin (hCG) is higher (1.31) than in the control group. For AFP 15.3% of cases were below the 5th centile and