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First-trimester diagnosis on chorionic villi obtained by direct vision technique

✍ Scribed by Björn Gustavii; M. Alan Chester; Heléne Edvall; Serafim Iosif; Ulf Kristoffersson; Lars Löfberg; Anita Mineur; Felix Mitelman

Publisher: Springer
Year: 1984
Tongue: English
Weight: 414 KB
Volume: 65
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00291562

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✦ Synopsis

An improved technique for direct vision chorionic biopsy that gives a clear view of the amniotic sac was developed. With this technique, used in 48 women prior to vacuum aspiration and in six cases for diagnosis (karyotyping or enzyme analysis), it was possible to obtain chorionic villi free from contamination by maternal tissue. It was also possible to pick out villi (rich in blood vessels and with abundant buds on their surface) found to be most capable of growing in vitro. In the diagnostic cases, the pregnancies have continued uneventfully since the sampling; one pregnancy is now in the 32nd week.

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