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First Total Synthesis of Naturally Occurring (−)-Nitidon and Its Enantiomer

✍ Scribed by Fabio Bellina; Adriano Carpita; Luca Mannocci; Renzo Rossi


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
169 KB
Volume
2004
Category
Article
ISSN
1434-193X

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Stereoselective Total Synthesis of Natur
✍ Xiao-Long Du; Hong-Li Chen; Hui-Jin Feng; Yuan-Chao Li 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 German ⚖ 233 KB

## Abstract A practical stereoselective synthesis of (__S__)‐bakuchiol (**1**) and its enantiomer is reported. The important intermediate, (__R__)‐configured __β__‐siloxy aldehyde **5**, was obtained in three steps from the easily available material geraniol (**2**) __via__ the key step of __Yamamo