First Total Synthesis of (-)-Fumitremorg
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Pedro H.H. Hermkens; Ralf Plate; Harry C.J. Ottenheijm
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Article
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1988
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Elsevier Science
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French
β 983 KB
The fit total synthesk of the. tranorgic myamiin fumitranorgin C (la) m@iying a-mehxy-N-hydroxyqptophm (Sa) is pmmtat. Our qroach fatura formation of the nimnc (6a). steramlahe cyclowldition to yield 7a, ring openiq and couphg with an Lpmline daivative to form 14. Bwe-catalywd cpimairh gave 16. whic