First total synthesis and determination of the absolute configuration of strictifolione, a new 6-(ω-phenylalkenyl)-5,6-dihydro-α-pyrone, isolated from Cryptocarya strictifolia

✍ Scribed by Lia Dewi Juliawaty; Yoshimi Watanabe; Mariko Kitajima; Sjamsul Arifin Achmad; Hiromitsu Takayama; Norio Aimi

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 203 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)02181-0

✦ Synopsis

Starting from (S)-malic acid and (S)-glycidol, the first total synthesis of strictifolione, a new 6-(v-phenylalkenyl)-5,6dihydro-a-pyrone isolated from Cryptocarya strictifolia, was accomplished, which confirmed its structure including the absolute configuration of the asymmetric centers.