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First Synthesis of Bengazole A.

✍ Scribed by Mulder, Roger J.; Shafer, Cynthia M.; Molinski, Tadeusz F.

Book ID: 127327072
Publisher: American Chemical Society
Year: 2000
Tongue: English
Weight: 8 KB
Volume: 65
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo004032g

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## Abstract The bengazoles are a family of marine natural products that display potent antifungal activity and a unique structure, containing two oxazole rings flanking a single carbon atom. Total syntheses of bengazole A and B are described, which contain a sensitive stereogenic centre at this pos