First Synthesis, Isolation and Complete Characterization of Both Enantiomers of Inherently Chiral Resorc[4]arenes by Monofunctionalization

✍ Scribed by Ceno Agena; Christian Wolff; Jochen Mattay

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 288 KB
• Volume: 2001
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/1099-0690(200108)2001:15<2977::aid-ejoc2977>3.0.co;2-l

✦ Synopsis

The monofunctionalization of rccc-2,8,14,20-tetramethylresorc[4]arene (1) with (S)-(+)-10-camphorsulfonyl chloride led to a diastereomeric mixture of (+)-2a and (-)-2b, which were separated by HPLC. Permethylation of these compounds was [a