Synthesis of morphine-[N-methyl-14C]-6-β
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John R. Ferguson; Stephen J. Hollis; Grant A. Johnston; Keith W. Lumbard; Andrew
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Article
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2002
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John Wiley and Sons
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French
⚖ 95 KB
👁 1 views
## Abstract Protected morphine‐6‐glucuronide was converted into morphine‐[__N__‐methyl‐^14^C]‐6‐glucuronide by a three‐step procedure. Methyl (3‐pivaloylmorphin‐6‐yl 2,3,4‐tri‐__O__‐isobutyryl‐__β__‐D‐glucopyranosid)uronate was N‐demethylated by treatment with 1‐chloroethyl chloroformate to afford