First syntheses of natural products with the 2,7-dihydroxy-2H-1,4-benzoxazin-3(4H)-one skeleton
β Scribed by Michael Kluge; Holger Hartenstein; Achim Hantschmann; Dieter Sicker
- Book ID
- 112131178
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1995
- Tongue
- English
- Weight
- 695 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0022-152X
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2-Hydroxy-4,7-dimethoxy-2H-1,4-benzoxazin-3(4H)-one (8), the hitherto undescribed free hemiacetalic agiyeone of a benzoxazinoid acetal glucnside naturally occurring in wheat, has been synthesized following two pathways, independently. This cyclic hydroxamic acid methyl ester proved to be very unstab