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First successful application of preimplantation genetic diagnosis and haplotyping for congenital hyperinsulinism

✍ Scribed by Wafa Qubbaj; Abdulrahman Al-Swaid; Saad Al-Hassan; Khalid Awartani; Hesham Deek; Serdar Coskun


Book ID
118498577
Publisher
Reproductive Healthcare Ltd
Year
2011
Tongue
English
Weight
579 KB
Volume
22
Category
Article
ISSN
1472-6491

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Cystic fibrosis (CF) is an autosomal recessive disease characterized by obstruction and chronic infections of the respiratory tract and pancreatic insufficiency. The gene was cloned in 1989 and the most frequent mutation was shown to be the delta F508 mutation. During PGD, embryos obtained in vitro