First stereoselective total synthesis of trichodermone A
โ Scribed by Palakodety Radha Krishna; Raghu Ram Kadiyala
- Book ID
- 104098103
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 256 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
The first stereoselective total synthesis of trichodermone A using Baylis-Hillman and ring-closing metathesis (RCM) reactions as key steps is reported.
๐ SIMILAR VOLUMES
The first total synthesis of Goniothalesdiol A, isolated from the stems of Goniothalamus amuyon (Annonaceae) is reported. The C2 stereocentre and C3/C4 syn diol were created by a Sharpless kinetic resolution followed by acetonide formation. The tetrahydropyran ring was formed and the C6 stereocentre
The first stereoselective total synthesis of the natural product (+)-dodoneine is described involving a Crimmins aldol reaction and a Horner-Wadsworth-Emmons olefination as the key steps.