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First Stereoselective Total Synthesis and Biological Evaluation of Amphidinin B and Its Analogues

✍ Scribed by Jhillu S. Yadav; A. Srinivas Reddy; Ch. Suresh Reddy; Basi V. Subba Reddy; Venkateshwarlu Saddanapu; Anthony Addlagatta


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
640 KB
Volume
2011
Category
Article
ISSN
1434-193X

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Total Synthesis and Biological Evaluatio
✍ Alois FΓΌrstner; Susanne FlΓΌgge; Oleg Larionov; Yohei Takahashi; Takaaki Kubota; πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 766 KB

## Abstract **The awesome power of metathesis** is illustrated by a concise synthesis of the extremely scarce marine natural product amphidinolide V, which hinges on a sequence of ring‐closing alkyne metathesis followed by intermolecular enyne metathesis with ethylene (see scheme). As a complete se