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First-Principles Prediction of the Sequence-Dependent Stability of RNA Hairpin Loop

✍ Scribed by Liu, Liang; Chen, Shi-Jie

Book ID
122263459
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
35 KB
Volume
98
Category
Article
ISSN
0006-3495

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πŸ“œ SIMILAR VOLUMES

The stability of RNA hairpin loops conta
The stability of RNA hairpin loops containing A–U–G: An–U–G–Um
✍ Eric Wickstrom; Ignacio Tinoco Jr. πŸ“‚ Article πŸ“… 1974 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 875 KB

RNA oligomers with the sequence AJJ-G-Urn, n = 7-9, m = 5-10, have been synthesized and found to form hairpin loops in 21 mM or 101 mM Na+. The hairpin loops displayed melting temperatures 13'-29'C greater than that of the hairpin loop AsCs-U6 in the same solvent. The increased stability of these ha