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First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics

✍ Scribed by Wu, Baojian (author);Kulkarni, Kaustubh (author);Basu, Sumit (author);Zhang, Shuxing (author);Hu, Ming (author)

Book ID: 102912808
Publisher: John Wiley and Sons Inc.
Year: 2011
Tongue: English
Weight: 901 KB
Volume: 100
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.22568

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## Abstract The pharmacokinetics of L‐FMAUS after intravenous and oral administration (20, 50 and 100 mg/kg) to rats, gastrointestinal first‐pass effect of L‐FMAUS (50 mg/kg) in rats, __in vitro__ stability of L‐FMAUS, blood partition of L‐FMAUS between plasma and blood cells of rat blood, and prot