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First-in-class approval rate stays steady


Book ID
121011857
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
99 KB
Volume
12
Category
Article
ISSN
1474-1776

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Theoretical decrease in systemic availab
โœ John G. Wagner; Edward J. Antal; Alfred T. Elvin; William R. Gillespie; Evelyn A ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 118 KB ๐Ÿ‘ 1 views

KEY WORDS Systemic availability Michaelis-Menten kinetics Sinusoidal perfusion model THEORETICAL Equation (1) is the general ~n e ' -~ which relates all important variables of the sinusoidal perfusion model for the steady-state situation, where v is the velocity of metabolism of the drug in the liv