## Abstract We have engineered a scaffold constructed of synthetic octacalcium phosphate (OCP) and porcine collagen sponge (OCP/Col), and reported that OCP/Col drastically enhanced bone regeneration. In this study, we investigated whether OCP/Col would enhance bone regeneration more than Ξ²βtricalci
β¦ LIBER β¦
First Clinical Application of Octacalcium Phosphate Collagen Composite in Human Bone Defect
β Scribed by Kawai, Tadashi; Echigo, Seishi; Matsui, Keiko; Tanuma, Yuji; Takahashi, Tetsu; Suzuki, Osamu; Kamakura, Shinji
- Book ID
- 121402705
- Publisher
- Mary Ann Liebert
- Year
- 2014
- Tongue
- English
- Weight
- 742 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1937-3341
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Diaphyseal segmental defects in the tibia of 18 sheep were used to evaluate the healing potential of a composite bone substitute device (CBS) composed of a tricalcium phosphate cylinder (TCP), naturally occurring sheep bone morphogenetic protein (sBMP), and type IV collagen. A total of 100 mg of sBM