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First Case of Ring-Chain Tautomerism of N-Unsubstituted 1,2,3,4-Tetrahydroquinazolines

โœ Scribed by K. N. Zelenin; A. A. Potapov; I. V. Lagoda; V. V. Alekseev; J. Sinkkonen; K. Pihlaja


Book ID
110405871
Publisher
Springer US
Year
2002
Tongue
English
Weight
102 KB
Volume
38
Category
Article
ISSN
0009-3122

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Thiohydrazide compounds 1 react with lactam acetals 2 or solution, however, most of them undergo a reversible ringlactim ethers 3 by condensation giving unusual zwitterionic chain transformation to novel 2-(o-aminoalkyl)-1,3,4-thiaditautomers 5 of lactam thioacylhydrazones 4. These compounds azole s