Cover
Title Page
Copyright Page
Dedication
Contents
Contributing Authors
Faculty Reviewers
Preface
Acknowledgements
How to Contribute
SECTION I GENERAL PRINCIPLES
Chapter 1, Biochemistry
Case 1: Alkaptonuria
Case 2: Ataxia-Telangiectasia
Case 3: Cyanide Poisoning
Case 4: Down Syndrome
Case 5: Duchenne Muscular Dystrophy
Case 6: Ehlers-Danlos Syndrome
Case 7: Familial Hypercholesterolemia
Case 8: Fragile X Syndrome
Case 9: Fructose Intolerance
Case 10: Homocystinuria
Case 11: Hurler Syndrome
Case 12: Kartagener Syndrome
Case 13: Lesch-Nyhan Syndrome
Case 14: McArdle Disease
Case 15: Phenylketonuria
Case 16: Pyruvate Dehydrogenase Deficiency
Case 17: Tay-Sachs Disease
Case 18: Vitamin B1 Deficiency
Case 19: Wiskott-Aldrich Syndrome
Chapter 2, Immunology
Case 1: Contact Dermatitis
Case 2: DiGeorge Syndrome
Case 3: Guillain-Barre Syndrome
Case 4: Hemolytic Uremic Syndrome
Case 5: Immunoglobulin A Deficiency
Case 6: Onchocerciasis
Case 7: Osteomyelitis
Case 8: Pneumocystis jiroveci Pneumonia
Case 9: Primary Tuberculosis
Case 10: Pseudomonas aeruginosa Infection
Case 11: Schistosomiasis
Case 12: Transplant Reaction
Case 13: Toxic Shock Syndrome
Chapter 3, Microbiology
Case 1: Acanthamoeba Infection
Case 2: Actinomyces Versus Nocardia
Case 3: Anaphylaxis
Case 4: Anthrax
Case 5: Ascariasis
Case 6: Aspergillosis
Case 7: Botulism
Case 8: Candidiasis
Case 9: Chagas Disease
Case 10: Cholera
Case 11: Chronic Granulomatous Disease
Case 12: Clostridium difficile Infection
Case 13: Congenital Syphilis
Case 14: Creutzfeldt-Jakob Disease
Case 15: Cryptococcal Meningitis
Case 16: Cysticercosis
Case 17: Cytomegalovirus Infection
Case 18: Dengue Fever
Case 19: Diphtheria
Case 20: Elephantiasis
Case 21: Giardiasis
Case 22: Group B Streptococcus Infection in Infants
Case 23: Hand, Foot, and Mouth Disease
Case 24: Herpes Simplex Virus Type 2 Infection
Case 25: Hookworm Infection
Case 26: Influenza Virus Infection
Case 27: Kaposi Sarcoma
Case 28: Legionnaires Disease
Case 29: Leprosy
Case 30: Listeria Meningitis
Case 31: Liver Cysts: Echinococcus Infection
Case 32: Lyme Disease
Case 33: Malaria
Case 34: Measles
Case 35: Mononucleosis
Case 36: Mucormycosis
Case 37: Mumps
Case 38: Neisseria gonorrhoeae and Septic Arthritis
Case 39: Neisseria meningitidis Meningitis
Case 40: Pinworm Infection
Case 41: Rabies
Case 42: Ringworm
Case 43: Rocky Mountain Spotted Fever
Case 44: Shingles
Case 45: Strongyloidiasis
Case 46: System Mycoses
Case 47: Toxoplasmosis
Case 48: Visceral Leishmaniasis
Case 49: Yellow Fever
Chapter 4, Pharmacology
Case 1: Acetaminophen Overdose
Case 2: Agranulocytosis Secondary to Drug Toxicity
Case 3: Barbiturate Versus Benzodiazepine
Case 4: ?-Adrenergic Second Messenger Systems
Case 5: Drug-Induced Lupus and Liver Metabolism
Case 6: Drug Development
Case 7: Ethylene Glycol Poisoning
Case 8: Lead Poisoning
Case 9: Monoamine Oxidase Inhibitor
Case 10: Neuromuscular Blocking Drugs
Case 11: Organophosphates and Cholinergic Drugs
Case 12: Pharmacodynamics
Case 13: Pharmacokinetics
Chapter 5, Public Health Sciences
Case 1: Alcohol Withdrawal
Case 2: Benzodiazepine Overdose
Case 3: Delirium
Case 4: Drug Toxidromes
Case 5: Eating Disorders
Case 6: Ethical Principles
Case 7: Evaluation of Diagnostic Tests
Case 8: Management of End-of-Life Care
Case 9: Medicare
Case 10: Milestones of Development
Case 11: Narcolepsy
Case 12: Operant Conditioning
Case 13: Opioid Intoxication
Case 14: Physician Confidentiality and Domestic Violence
Case 15: Statistical Bias
Chapter 6, Cardiovascular
Case 1: Abdominal Aortic Aneurysm
Case 2: Aortic Stenosis
Case 3: Atherosclerosis/Acute Coronary Syndrome
Case 4: Atrial Fibrillation
Case 5: Atrial Myxoma
Case 6: Atrioventricular Block
Case 7: Cardiac Anatomy and Biomarkers
Case 8: Coarctation of the Aorta
Case 9: Congenital Rubella
Case 10: Deep Venous Thrombosis
Case 11: Dilated Cardiomyopathy
Case 12: Endocarditis
Case 13: Granulomatosis with Polyangiitis (Wegener Granulomatosis)
Case 14: Heart Failure
Case 15: Hypertension
Case 16: Hypertrophic Cardiomyopathy
Case 17: Kawasaki Disease
Case 18: Mesenteric Ischemia
Case 19: Mitral Valve Prolapse
Case 20: Myocardial Infarction
Case 21: Patent Ductus Arteriosus
Case 22: Pericarditis
Case 23: Polyarteritis Nodosa
Case 24: Rheumatic Heart Disease
Case 25: Temporal Arteritis
Case 26: Tetralogy of Fallot
Case 27: Truncus Arteriosus
Case 28: Unstable Angina
Case 29: Wolff-Parkinson-White Syndrome
Chapter 7, Endocrine
Case 1: Adrenal Insufficiency
Case 2: Congenital Adrenal Hyperplasias
Case 3: Cushing Syndrome and Glucocorticoid Excess
Case 4: Graves Disease
Case 5: Growth Hormone Excess, Gigantism, and Acromegaly
Case 6: Hyperparathyroidism
Case 7: Hypothyroidism
Case 8: Metabolic Syndrome
Case 9: Multiple Endocrine Neoplasia
Case 10: Primary Hyperaldosteronism
Case 11: Pseudohypoparathyroidism
Case 12: Pheochromocytoma
Case 13: Sheehan Syndrome
Case 14: Syndrome of Inappropriate Antidiuretic Hormone
Case 15: Thyroglossal Duct Cyst
Case 16: Thyroid Cancer
Case 17: Toxic Multinodular Goiter
Case 18: Type 1 Diabetes Mellitus and Diabetic Ketoacidosis
Case 19: Type 2 Diabetes Mellitus
Case 20: Thyroidectomy
Chapter 8, Gastrointestinal
Case 1: Achalasia
Case 2: Acute Pancreatitis
Case 3: Alcoholic Cirrhosis of the Liver
Case 4: Appendicitis
Case 5: Cholangitis
Case 6: Crigler-Najjar Syndrome and Hereditary Hyperbilirubinemias
Case 7: Diverticulitis
Case 8: Esophageal Atresia with Tracheoesophageal Fistula
Case 9: Gallstones (Cholelithiasis)
Case 10: Gastric Carcinoma
Case 11: Gastrinoma
Case 12: Gastroesophageal Reflux Disease and Barrett Esophagus
Case 13: Hemochromatosis
Case 14: Hepatitis B Virus Infection
Case 15: Hepatitis C Virus Infection
Case 16: Hepatocellular Carcinoma
Case 17: Hyperbilirubinemia
Case 18: Inflammatory Bowel Diseases
Case 19: Intussusception and Meckel Diverticulum
Case 20: Lower Gastrointestinal Bleeding/Diverticulosis
Case 21: Primary Biliary Cirrhosis
Case 22: Primary Hepatocellular Carcinoma
Case 23: Pseudomembranous Colitis and Clostridium difficile Infection
Case 24: Pyloric Stenosis
Case 25: Reye Syndrome
Case 26: Short Bowel Syndrome
Case 27: Upper Gastrointestinal Bleed
Case 28: Vitamin B12 Deficiency
Case 29: Vitamin B3 Deficiency
Case 30: Zollinger-Ellison Syndrome
Chapter 9, Hematology and Oncology
Case 1: Acute Intermittent Porphyria
Case 2: Acute Lymphoblastic Leukemia
Case 3: Acute Myelogenous Leukemia
Case 4: Anatomy of Spleen
Case 5: Anemias: Aplastic Anemia
Case 6: Anemias: Iron Deficiency Anemia
Case 7: Anemias: Macrocytic Anemia
Case 8: Anemias: Sickle Cell Anemia
Case 9: Anemias: Warm Autoimmune Hemolytic Anemia
Case 10: Breast Cancer
Case 11: Burkitt Lymphoma and Tumor Lysis Syndrome
Case 12: Carcinoid Syndrome
Case 13: Chronic Myelogenous Leukemia
Case 14: Colorectal Cancer
Case 15: Disseminated Intravascular Coagulation
Case 16: Gastric Cancer
Case 17: Glucose-6-Phospate Dehydrogenase Deficiency
Case 18: Head and Neck Squamous Cell Tumor
Case 19: Hereditary Hemochromatosis
Case 20: Hodgkin Lymphoma
Case 21: Idiopathic Thrombocytopenic Purpura
Case 22: Hereditary Spherocytosis
Case 23: Lead Poisoning
Case 24: Lung Cancer
Case 25: Multiple Myeloma
Case 26: Neuroblastoma
Case 27: Oligodendroglioma
Case 28: Ovarian Cancer
Case 29: Pancreatic Cancer
Case 30: Platelet and Coagulation Disorders and Hemophilia
Case 31: Polycythemia Vera
Case 32: Retinoblastoma
Case 33: Small Cell Lung Cancer
Case 34: Teratoma
Case 35: Testicular Cancer
Case 36: Thalassemias
Case 37: Thrombotic Thrombocytopenic Purpura and Hemolytic-Uremic Syndrome
Case 38: Von Willebrand Disease
Chapter 10, Musculoskeletal, Skin, and Connective Tissue
Case 1: Abdominal and Peritoneum Anatomy
Case 2: Anatomy of Thorax
Case 3: Costochondritis
Case 4: Ewing Sarcoma
Case 5: Gout
Case 6: Hip Fracture
Case 7: Inguinal Hernias
Case 8: Klumpke Palsy
Case 9: Knee Anatomy
Case 10: Melanoma
Case 11: Muscular Dystrophies
Case 12: Osteoarthritis
Case 13: Neurofibromatosis
Case 14: Osteogenesis Imperfecta
Case 15: Osteoporosis
Case 16: Rheumatoid Arthritis
Case 17: Rotator Cuff Tear
Case 18: Squamous Cell Carcinoma
Case 19: Systemic Lupus Erythematosus
Case 20: Systemic Sclerosis
Chapter 11, Neurology and Special Senses
Case 1: Alzheimer Disease
Case 2: Amyotrophic Lateral Sclerosis
Case 3: Acute Otitis Media
Case 4: Brown-Sรฉquard Syndrome
Case 5: Central Cord Syndrome
Case 6: Corneal Abrasion and Eye Injury
Case 7: Craniopharyngioma
Case 8: Femoral Neuropathy
Case 9: Glioblastoma Multiforme
Case 10: Guillain-Barrรฉ Syndrome
Case 11: Hearing Loss
Case 12: Homonymous Hemianopia and Visual Field Defects
Case 13: Horner Syndrome
Case 14: Huntington Disease
Case 15: Hydrocephalus
Case 16: Macular Degeneration
Case 17: Medulloblastoma
Case 18: Meningioma
Case 19: Metastatic Brain Tumor
Case 20: Migraine Headache
Case 21: Multiple Sclerosis
Case 22: Myasthenia Gravis
Case 23: Neurofibromatosis Type 1
Case 24: Neurofibromatosis Type 2 and Hearing Loss
Case 25: Open-Angle Glaucoma
Case 26: Parkinson Disease
Case 27: Pituitary Adenoma
Case 28: Recurrent Laryngeal Nerve Injury
Case 29: Seizure
Case 30: Spinal Cord Compression due to Metastatic Cancer
Case 31: Stroke
Case 32: Sturge-Weber Syndrome
Case 33: Subarachnoid Hemorrhage
Case 34: Subdural Hematoma
Case 35: Transient Ischemic Attack
Case 36: Syncope
Case 37: Tuberous Sclerosis
Case 38: Ulnar Neuropathy
Case 39: Vascular Dementia
Case 40: Viral Meningitis
Case 41: Von HippelโLindau Disease
Case 42: Wernicke Encephalopathy and Vitamin B1 Deficiency
Chapter 12, Psychiatry
Case 1: Attention-Deficit Hyperactivity Disorder
Case 2: Bipolar Disorder
Case 3: Generalized Anxiety Disorder
Case 4: Major Depressive Disorder
Case 5: Obsessive-Compulsive Disorder
Case 6: Obsessive-Compulsive Personality Disorder
Case 7: Panic Disorder
Case 8: Post-traumatic Stress Disorder
Case 9: Schizophreniform Disorder
Case 10: Somatic Symptom Disorder
Case 11: Steroid-Induced Mania
Case 12: Tardive Dyskinesia
Case 13: Tourette Syndrome
Chapter 13, Renal
Case 1: Acute Interstitial Nephritis
Case 2: Acute Pyelonephritis
Case 3: Acute Tubular Necrosis
Case 4: Autosomal Dominant Polycystic Kidney Disease
Case 5: Fanconi Syndrome
Case 6: Goodpasture Syndrome
Case 7: Henoch-Schรถnlein Purpura
Case 8: Hereditary Nephritis (Alport Syndrome)
Case 9: Hypercalcemia
Case 10: Hypokalemia
Case 11: Hyponatremia
Case 12: Hyponatremia
Case 13: Hypophosphatemic Rickets
Case 14: Metabolic Acidosis with Respiratory Alkalosis
Case 15: Metabolic Alkalosis
Case 16: Nephrolithiasis
Case 17: Nephrotic Syndrome: Focal Segmental Glomeruloscleritis
Case 18: Nephrotic Syndrome: Minimal Change Disease
Case 19: Rapidly Progressive Glomerulonephritis
Case 20: Renal Artery Stenosis
Case 21:Transplant Immunology
Case 22: Vesicoureteral Reflux
Chapter 14, Reproductive
Case 1: Abruptio Placentae
Case 2: Androgen Insensitivity Syndrome
Case 3: Bacterial Vaginosis
Case 4: Benign Prostatic Hyperplasia
Case 5: Breast Mass
Case 6: Ectopic Pregnancy
Case 7: Endometriosis
Case 8: Erectile Dysfunction
Case 9: Gestational Diabetes Mellitus
Case 10: Hydatidiform Mole
Case 11: Klinefelter Syndrome
Case 12: Leiomyoma
Case 13: Menopause
Case 14: Ovarian Cancer
Case 15: Paget Disease of the Breast
Case 16: Pelvic Inflammatory Disease
Case 17: Preeclampsia
Case 18: Testicular Torsion
Case 19: Turner Syndrome
Chapter 15, Respiratory
Case 1: Acute Epiglottitis
Case 2: Acute Respiratory Distress Syndrome
Case 3: Anatomy of Lung
Case 4: Asthma Exacerbation
Case 5: Bronchiectasis
Case 6: Carbon Monoxide Poisoning
Case 7: Chronic Obstructive Pulmonary Disease
Case 8: Cystic Fibrosis
Case 9: Emphysema
Case 10: Neonatal Respiratory Distress Syndrome
Case 11: Pleural Effusion
Case 12: Pneumoconioses
Case 13: Pneumonia: Community-Acquired Pneumonia
Case 14: Pneumonia: Mycoplasma pneumoniae Infection
Case 15: Pneumothorax
Case 16: Respiratory Acidosis
Case 17: Sarcoidosis
Case 18: Small Cell Lung Cancer
Case 19: Venous Thromboembolism
Appendix: Case Index
Index
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
About the Editors
