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Fine Tuning of Calmodulin's Affinity for Ca2+ by Target Proteins

✍ Scribed by Zhang, Miao; Zhang, Ji-Fang


Book ID
122332188
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
40 KB
Volume
102
Category
Article
ISSN
0006-3495

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Minimal residues in linker domain of syn
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## Abstract The linker domain is important for the conformational change syntaxin 1A, which enables it to act as a SNARE for exocytosis. We found that when applied exogenously, the linker domain is a potent inhibitor of exocytosis through inhibiting interaction between autophosphorylated CaMKII and