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Fine structure of the ura 2 locus in Saccharomyces cerevisiae

✍ Scribed by Denis-Duphil, Michèle ;Lacroute, François

Publisher
Springer
Year
1971
Tongue
English
Weight
739 KB
Volume
112
Category
Article
ISSN
0026-8925

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✍ Lee, Grace S. -F. ;Savage, Elizabeth A. ;Ritzel, R. Gary ;von Borstel, R. C. 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 891 KB

A forward mutation system has been developed to obtain rapidly clonable mutants at the URA3 locus in yeast by means of selection for 5-fluoroorotic acid resistance. We have used this system to determine base changes in 35 spontaneous and 34 ultraviolet radiation-induced ura3 base substitution mutant