Fine-needle aspiration cytology of ductal adenoma: Report of a case associated with a mucocele-like lesion

✍ Scribed by Clara E. Mesonero; Sana Tabbara

• Publisher: John Wiley and Sons
• Year: 1995
• Tongue: English
• Weight: 818 KB
• Volume: 13
• Category: Article
• ISSN: 8755-1039
• DOI: 10.1002/dc.2840130313

✦ Synopsis

Ductal adenoma (DA) is an uncommon breast lesion that can histologically and clinicah) mimic carcinoma. We performed a fine-needle aspiration (FNA) of a DA. Cytologically, the lesion hadfeatures overlapping with those of mucinous carcinoma (MC), mucoceie-like lesion, lactating adenoma (LA), and in retrospect with intraductal papilloma (IP). The smears were highly cellular and contained numerous monolayered sheets of ductal cells with prominent punched-out, small vacuoles distending the cytoplasm. The nuclei were mostly round to oval and had bland chromatin. Occasionally celI.9 with enlarged nuclei and conspicuous nucleoli were present. The background showed large mucin pools, scattered single cells with mild nuclear atypia, some with apocrine metplasia, rare strbped nuclei, and a fibrovascular stromal componen t. Calcifications were also present.

We compure our cytologic findings with those of the lesions considered in the difermtial diagnosis. Due to its rare incidence and unusual features, DA may represent a diagnostic pitfall on