Fine needle aspiration biopsy in the diagnosis of thyroid cancer and thyroid disease

✍ Scribed by Federico Hawkins; Diego Bellido; Carmen Bernal; Demetra Rigopoulou; Maria Pilar Ruiz Valdepeñas; Esperanza Lazaro; Andres Perez-Barrios; Pedro De Agustin

• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: English
• Weight: 412 KB
• Volume: 59
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(19870315)59:6<1206::aid-cncr2820590629>3.0.co;2-7

✦ Synopsis

Fine needle aspiration biopsy (FNAB) performed for diffuse and nodular goiter in the past 5 years, was evaluated in 1399 cases. Surgery was performed on the basis of FNAB cytologic diagnosis that was positive or suggestive of malignancy and/or a suggestive clinical history. Surgery also was performed in cases of cold nodules with negative FNAB results that did not respond to 6 months of suppressive thyroxine therapy. A correlation of cytologic findings with histologic findings was possible in 415 patients who underwent surgery: the evaluation of FNAB results yielded better results when suspicious cytologic findings were considered to be positive (2.4% false-negative, 86.3% sensitivity) rather than negative (6.5% and 65.78, respectively). FNAB has become a useful procedure in the study and diagnosis of thyroid diseases. It is a simple, rapid diagnostic procedure that may be used to expedite the management ofmalignant lesions.