Fine-needle aspiration as the initial diagnostic modality in malignant lung disease

✍ Scribed by Walter Blumenfeld; Michael Singer; Sidney Glanz; Man Hon

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 473 KB
• Volume: 14
• Category: Article
• ISSN: 8755-1039
• DOI: 10.1002/(sici)1097-0339(199604)14:3<268::aid-dc14>3.0.co;2-j

✦ Synopsis

Cytologic detection of lung cancer is accepted, accurate, and timehonored. Typically, cytologic workup of a radiologic abnormality proceeds sequentially from sputum to bronchoalveolar cytology, and, if necessary, to fine-needle aspiration biopsy (FNA). Initial use of FNA in lung cancer diagnosis is controversial, but increasingly popular. We therefore decided to objectively assess current practice in cytologic lung cancer diagnosis at our institution. AN pulmonary cytologic diagnoses for 1993 and the first halfof 1994 were retrieved. Positive diagnoses were then used to access all patient data. Patients were stratified according to the specimen from which the first positive diagnosis was obtained. Of 542 pulmonary cytology specimens, 15% were sputa, 65% were bronchoalveolar, and 20% were FNAs. One hundred sixty-one of 172 malignant diagnoses were first diagnoses. Three percent of first malignant diagnoses were made from sputa, 47% were from lavages, and 50% were from FNAs. Although FNAs comprised just 20% of all pulmonary cytologies, 50% of all new malignant Cytologic diagnoses were made by FNA. Initial use of FNA is successful, has a high diagnostic yield and low complication rate, and offers the most direct approach to diagnosis. Diagn Cytopa-