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Fine mapping of multiple sclerosis susceptibility genes provides evidence of allelic heterogeneity at the IL2RA locus

โœ Scribed by Devindri Perera; Jim Stankovich; Helmut Butzkueven; Bruce V. Taylor; Simon J. Foote; Trevor J. Kilpatrick; Justin P. Rubio


Book ID
113730464
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
674 KB
Volume
211
Category
Article
ISSN
0165-5728

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Objective. Autoimmune diseases often have susceptibility genes in common, indicating similar molecular mechanisms. Increasing evidence suggests that rs6822844 at the IL2-IL21 region is strongly associated with multiple autoimmune diseases in individuals of European descent. This study was undertaken