Fine mapping of a schizophrenia susceptibility locus at chromosome 6q23: increased evidence for linkage and reduced linkage interval
β Scribed by Levi, Adi; Kohn, Yoav; Kanyas, Kyra; Amann, Daniela; Pae, Chi-Un; Hamdan, Adnan; Segman, Ronnen H; Avidan, Nili; Karni, Osnat; Korner, Mira
- Book ID
- 110026310
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 130 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1018-4813
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## Recent reports on potential linkage by Faraone and the NIMH Genetics Initiative-Millennium Schizophrenia Consortium [1997: Am J Med Genet 74:557], and by Straub et al. [1997: Am J Med Genet 74:558], prompted us to study chromosome 10 in a sample of 72 families containing 2 or more affected sibs
## Abstract Linkage and association studies in schizophrenia have repeatedly drawn attention to several chromosomal regions and to genes within them. Conflicting patterns of association and the lack of a clear functional significance of the associated variants limit the interpretation of these resu