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Fine mapping of a schizophrenia susceptibility locus at chromosome 6q23: increased evidence for linkage and reduced linkage interval

✍ Scribed by Levi, Adi; Kohn, Yoav; Kanyas, Kyra; Amann, Daniela; Pae, Chi-Un; Hamdan, Adnan; Segman, Ronnen H; Avidan, Nili; Karni, Osnat; Korner, Mira


Book ID
110026310
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
130 KB
Volume
13
Category
Article
ISSN
1018-4813

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## Recent reports on potential linkage by Faraone and the NIMH Genetics Initiative-Millennium Schizophrenia Consortium [1997: Am J Med Genet 74:557], and by Straub et al. [1997: Am J Med Genet 74:558], prompted us to study chromosome 10 in a sample of 72 families containing 2 or more affected sibs

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## Abstract Linkage and association studies in schizophrenia have repeatedly drawn attention to several chromosomal regions and to genes within them. Conflicting patterns of association and the lack of a clear functional significance of the associated variants limit the interpretation of these resu