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Fine deletion mapping of chromosome 2q21-37 shows three preferentially deleted regions in oral cancer

✍ Scribed by Beyhan Cengiz; Mehmet Gunduz; Hitoshi Nagatsuka; Levent Beder; Esra Gunduz; Ryo Tamamura; Naila Mahmut; Kunihiro Fukushima; Mahmoud Al Sheikh Ali; Yoshio Naomoto; Kenji Shimizu; Noriyuki Nagai


Book ID
118492278
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
658 KB
Volume
43
Category
Article
ISSN
1368-8375

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Loss of heterozygosity (LOH) on 3p is frequent in human renal cell carcinomas, lung cancers, and breast cancers. To define the region(s) on 3p that harbor presumptive tumor suppressor gene(s) for breast cancer, we examined 196 primary breast tumors for their patterns of LOH at 22 microsatellite mark