𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Finding genes that underlie cancer using genetic tools

✍ Scribed by Ángel Carracedo


Book ID
107596105
Publisher
Springer Milan
Year
2006
Tongue
Spanish
Weight
348 KB
Volume
8
Category
Article
ISSN
1699-048X

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The bacterial enzyme cytosine deaminase (CD) catalyzes the conversion of 5-fluorocytosine (5-FC) to the lethal 5-fluorouracil (5-Fu) and so provides a useful system for selective killing of gene-modified mammalian tumor cells. Cloning of the CD gene from Escherichiu coli and expression in human tumo