β Scribed by Andy de Laet; Jurriaan J. J. Hehenkamp; Richard L. Wife
No coin nor oath required. For personal study only.
There are many opportunities for chemists to help make the drug discovery process more efficient. The virtual world of chemistry contains many challenges to the heterocyclic chemist but this world is very large and attention must be focused on the best candidates for synthesis and testing. The algorithm set SORT&gen makes it possible to form an opinion about the constitution of large compound collections. It also generates the ring scaffolds of the molecules that are missing in these collections. Its application in the drug discovery process is discussed and the smallest missing molecular scaffolds are presented.
π SIMILAR VOLUMES
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence