Benign prostatic hyperplasia (BPH) is a disease diagnosed by the presence of prostatic enlargement and lower-tract urinary obstruction. Finasteride (Proscar@), is a potent and specific inhibitor of 5a-reductase, which inhibits the conversion of testosterone (T) to dihydrotestosterone (DHT) an import
โฆ LIBER โฆ
Finasteride: A slow-binding 5.alpha.-reductase inhibitor
โ Scribed by Faller, Bernard; Farley, David; Nick, Hanspeter
- Book ID
- 111944525
- Publisher
- American Chemical Society
- Year
- 1993
- Tongue
- English
- Weight
- 761 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0006-2960
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In genetic male fetuses, dihydrotestosterone (DHT) plays an important role in normal prostatic and external genital differentiation. The enzyme steroid 5-alpha reductase (5 alpha R) catalyzes the conversion of testosterone (T) to DHT. The importance of 5 alpha R in sexual differentiation is evident
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