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Film diffusion studies of immobilized catalase in tubular flow reactors

✍ Scribed by Alan D. Traher; J. R. Kittrell


Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
182 KB
Volume
16
Category
Article
ISSN
0006-3592

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✦ Synopsis


Film Di#usion Studies of Immobilized Catalase in Tubular Flow Reactors

Recently, Rovito and Kittrelll have shown that glucose oxidase immobilized on porous glass exhibits film diffusional properties predictable by the McCune-Wilhelm correlation. In the present communication, it is shown that this a priori prediction method for film diffusion in tubular reactors is readily extended to an entirely different enzyme-support system, catalase on nickel-silica alumina. Excellent agreement of the experimental data with the correlation is demonstrated at 5"C, particle Reynolds numbers ranging from 7.3 to 119, and a t a feed hydrogen peroxide concentration of lO-4M.

EXPERIMENTAL

A continuous flow, tubular reactor similar to that described by Rovito and Kittrelll was used for the present study. Quantities of catalyst (catalase on nickel-silica alumina) ianging from 2.5 to 4.65 g were evaluated in 5 and 7 mm diameter glass reactors. The catalyst bed, consisting of a particle diameter range from 500 to 1000 microns, was supported by a stainless steel screen.

The silica alumina used in these studies was obtained from Norton Company (stock no. LA 3032), and had a surface area of 21.8 m*/g and an average pore diameter of 35.1 microns. The silica alumina was impregnated by nickel to the 6.4% (wt.) level, using the nickel nitrate procedure previously discussed.2 The nickel-silica alumina support was then silanized with 10% r-aminopropyltriethoxysilane in toluene and refluxed for 24 hr in chloroform containing 10% thiophosgene. The support was then contacted with 3600 u of beef liver catalase