Filling the gap: Chemistry of 3,5-bis(trifluoromethyl)-1H-pyrazoles
β Scribed by Angelo Maspero; Giovanni B. Giovenzana; Damiano Monticelli; Silvia Tagliapietra; Giovanni Palmisano; Andrea Penoni
- Book ID
- 113711655
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 261 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0022-1139
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π SIMILAR VOLUMES
This study describes, firstly, the synthesis of a new precursor, 4,6,6-trimethoxy-1,1,1-trifluorohex-3-en-2-one (1), from the trifluoroacetylation reaction of 1,1,3,3-tetramethoxybutane, in 65% yields. Afterwards, the reaction of 1 with two hydrazines (NH 2 NHR, where R = 2-furanoyl, C 6 F 5 ) led t
Two new series of 1,1 0 -carbonyl-bis[3-aryl(heteroaryl)-5-trihalomethyl-1H-pyrazoles], where aryl ΒΌ C 6 H 5 , 4-CH 3 C 6 H 4 , 4-FC 6 H 4 , 4-OCH 3 C 6 H 4 , 4-NO 2 C 6 H 4 , 4,4 0 -BiPh, 1-naphthyl, and heteroaryl ΒΌ 2thienyl and 2-furyl have been synthesized, in a one-pot methodology, from the rea