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Filaggrin Mutations are Associated with an Increased Risk of Infantile Food Allergy and Sensitization

✍ Scribed by Tan, T.; Ellis, J.A.; Koplin, J.J.; Martin, P.E.; Dang, T.D.; Matheson, M.C.; Dharmage, S.; Lowe, A.; Tang, M.; Robinson, M.; Ponsonby, A.; Osborne, N.; Hill, D.; Allen, K.J.


Book ID
119285831
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
40 KB
Volume
129
Category
Article
ISSN
1097-6825

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LRRK2 G2019S mutations are associated wi
✍ Rachel Saunders-Pullman; Matthew J. Barrett; Kaili M. Stanley; Marta San Luciano πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 70 KB

## Abstract Leucine rich repeat kinase (__LRRK2__) G2019S mutations are presumed to cause PD through a toxic gain of function of the protein kinase. Small molecule kinase inhibitors have been developed for the treatment of certain cancers, and some antioncogenic agents such as sunitinib, may nonspe