✦ LIBER ✦

Fighting cancer with viruses

✍ Scribed by S.C. Ferreira Jr.; M.L. Martins; M.J. Vilela

Book ID: 103881575
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 415 KB
Volume: 345
Category: Article
ISSN: 0378-4371
DOI: 10.1016/j.physa.2004.07.013

No coin nor oath required. For personal study only.

✦ Synopsis

One of the most promising strategies to treat cancer is attacking it with viruses. Viruses can kill tumor cells specifically or act as carriers that deliver normal genes into cancer cells. A model for virotherapy of cancer is investigated and its predictions are in agreement with results obtained from experimental tumors. Furthermore, the model reveals an oscillatory (periodic or aperiodic) response of tumor cells and virus populations which may make clinical prognosis difficult. These results suggest the need for new in vivo and in vitro experiments aiming to detect this oscillatory response.

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