Field desorption mass spectrometry of ten medicinal carbamates

✍ Scribed by Doris J. Rouse; David A. Brent

• Publisher: John Wiley and Sons
• Year: 1974
• Tongue: English
• Weight: 438 KB
• Volume: 1
• Category: Article
• ISSN: 1076-5174
• DOI: 10.1002/bms.1200010409

✦ Synopsis

The field desorption mass spectra of ten medicinal carbamates-meprobamate, mebutamate, carisoprodol, emylcamate, bethanechol chloride, styramate, hydroxyphenamate, mephenesin carbamate, methocarbamol and chlorphenesin carbamate-were run and compared with their published electron impact spectra. Of the ten compounds run only emylcamate did not give a field desorption mass spectrum. All others gave abundant molecular ions, with the exception of bethanechol chloride which has a quarternary ammonium group and gave a field desorption spectrum characteristic of compounds possessing such a functional group. N o general characteristic fragmentation was attributed to the carbamate function in the field desorption mode. However, the ease of obtaining abundant molecular ions or quasimolecular ions makes the field desorption method a valuable complementary technique to electron impact studies of carbamates.