## Abstract To ascertain whether the fidelity of protein synthesis declines during cellular aging in vitro, we have developed a cellβfree protein synthesizing system from cultured human fibroblasts which actively incorporates phenylalanine into acidβinsoluble material upon addition of poly (U). The
β¦ LIBER β¦
Fidelity of histone synthesis in cultured human fibroblasts
β Scribed by J.H. Buchanan; A. Stevens
- Book ID
- 119024928
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- English
- Weight
- 778 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0047-6374
No coin nor oath required. For personal study only.
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Histone variant synthesis patterns from human diploid fibrobladike cells of different in vitro ages were determined during exponential growth, at confluence, and during low serum arrest. The results are reported as the ratios of H2A variant synthesis (H2A.1 and HZA.2iH2A.x and H2A.z) and H3 variant