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Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase

✍ Scribed by Tindall, Kenneth R.; Kunkel, Thomas A.


Book ID
120311761
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
807 KB
Volume
27
Category
Article
ISSN
0006-2960

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## Abstract DNA is being constantly damaged by endo‐ and exogenous agents such as reactive oxygen species, chemicals, radioactivity, and ultraviolet radiation. Additionally, DNA is inherently labile, and this can result in, for example, the spontaneous hydrolysis of the glycosidic bond that connect