Fibronectin synthesis by high glucose level mediated proliferation of mouse embryonic stem cells: Involvement of ANG II and TGF-β1

Synergistic effect of high glucose and A

Synergistic effect of high glucose and ANG II on proliferation of mouse embryonic stem cells: Involvement of PKC and MAPKs as well as AT1 receptor

✍ Yun Hee Kim; Ho Jae Han 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 397 KB

## Abstract This study examined the synergistic effect of high glucose levels and ANG II on proliferation and its related signal pathways using mouse embryonic stem (ES) cells. The combined use of a high glucose concentration (25 mM) and ANG II increased the level of [^3^H]thymidine/BrdU incorporat